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Research Grants

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Research Grants

Funds for the facility and development of the current research activities conducted by the Centre for Cardiovascular Research and Development American Heart of Poland were obtained from the Operational Programme Innovative Economy 2007-2013, co-financed under the European Regional Development Fund.



The main objective of the CBR research is to increase the competitiveness of science by creating organizational structures and procedures that will allow us for:
• enhancing the quality of study
• increase the participation of young scientists in the use of funds for science
• strengthening links between the science and the economy sector
• implementation of mechanisms to increase the level of application of research and development results in the industry practice

One source of funding for research grants are from the National Center for Research and Development. With these funds are financed research projects (grants), including:
• projects STRATEGMED in which AHP acts as LEADER or as a PARTNER
• project of Applied Research Programme, in which AHP is a PARTNER

InFlow

Development and introduction of the first Polish low-profile aortic valve implanted percutaneously

Project realised in the framework of the consortium CardValve, composed of: American Heart of Poland (consortium leader), Balton Ltd., Silesian Center for Heart Diseases, Centre of Polymer and Carbon Materials of the Polish Academy of Sciences, Silesian University of Technology, Innovations for Heart and Vessels Ltd., National Research Institute of Animal Production.

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Apollo

Development and Comprehensive Evaluation of the First Polish, Second Generation, Thin Strut Biodegradable Polymer and Elastic, Sirolimus Eluting Vascular Stent

Project realised in the framework of the consortium composed of: American Heart of Poland (consortium leader), Balton Ltd., Centre of Polymer and Carbon Materials of the Polish Academy of Sciences, Silesian University of Technology Faculty of Biomedical Engineering, Silesian Center for Heart Diseases, Military University of Technology, Innovations for Heart and Vessels Ltd.

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Research grants

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  • BSM STENT

    BSM STENT

    Obtaining of self-expanding, polymeric and biodegradable, drug-eluting vascular stents

    Project realised in the framework of the consortium composed of: Centre of Polymer and Carbon Materials of the Polish Academy of Sciences (leader), American Heart of Poland Inc, Innovations for Heart and Vessels Ltd.

    Total budget: eligible costs 4,75 million PLN, funding 3,94 million PLN

    AHP budget: eligible costs 2,24 million PLN, funding 1,45 million PLN

    Study period: 01.04.2015 - 31.03.2018

    The aim of the project is to produce a working prototype of bioresorbable, self-expanded intravascular stents with shape memory behaviour, releasing the drug to treat restenosis. The innovative micro-injection technique will be used for this production. After checking its medicinal suitability and behaviour with a preclinical trial on a pig model, all obtained during the research process results will provide for further clinical studies and will be base for the relevant implementation of the production of bioresorbable endovascular stents with shape memory.

  • Result of the offer for delivery of biodegradable tubes

    Result of the offer for delivery of biodegradable tubes.

    Result of the offer for delivery of biodegradable tubes.

    Result_of_the_offer_for_delivery_of_biodegradable_tubes.pdf

  • Monitel-HF

    Monitel-HF

    The use of teletransmission of medical data in patients with heart failure for improvement of quality of life and reduction of treatment costs

    Project realised in the framework of the consortium MONITEL-HF composed of Silesian Center for Heart Diseases, American heart of Poland Inc, Kardio-Med Silesia Ltd., Polish-Japanese Academy of Information Technology, Central Information Technology Center of Mining, Institute of Medical Technology and Equipment, ENTE Ltd., NOVUM.

    Total budget: eligible costs 19,3 million PLN, funding 15,4 million PLN

    AHP budget: eligible costs 1,4 million PLN, funding 0,7 million PLN

    Study period: 01.03.2014 - 31.11.2016

    The main technical aim of the project is developing a multifunctional, intelligent, mobile system which could be applied in cardiac telemetry. The contemporary existing systems are not able to work effectively in a long period of time; they require special installations and calibrations of the whole system, frequently using invasive measurement technologies.

    The essential problem in mobile telemetry is also the way of transmitting data as well as appropriate securing of measurement data and energy requirement. We are going to test the possibilities and usefulness of non-invasive measurement of the following parameters, among others: Velocity of pulse wave, Frequency of cardiac rhythm, Heart rhythm variability, Physical activity, Perspiration rate, Arterial blood saturation, The temperature of the breastbone skin surface, Fluid retention in thorax – impedance spectroscopy, Fluid retention in abdomen - impedance spectroscopy, Percentage of fat tissue in thorax, Percentage of fat tissue in abdomen, Stroke volume of the left ventricle, Systemic arteries resistance, Position of the body during the night, Reporting by means of linear scales (1-10): e.g. comfort of sleep appetite and other factors. A medium integrating biosensors, fixed on the patient will be developed, which will enable various biosensor configuration.

    The signals from biosensors will be sent to a data concentrator, which will be responsible for their further transmission to the central gathering system and analysing biomedical data.

  • Restore

    Restore

    The use of modern telemedicine technologies in an innovative optimal cardiac rehabilitation program in patients after myocardial revascularization

    Project realised in the framework of the consortium composed of: American Heart of Poland Inc, The Jerzy Kukuczka Academy of Physical Education in Katowice, AGH University of Science and Technology Faculty of Electronics, Automatic Control and Biomedical Engineering, Silvermedia Ltd., Innovations for Heart and Vessels Ltd., Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., Universitätsklinikum Carl Gustav Carus Dresden

    Total budget: eligible costs 15,9 million PLN, funding 13,5 million PLN

    AHP budget: eligible costs 5,68 million PLN, funding 3,82 million PLN

    Study period: 01.03.2016 - 31.12.2019

    The project involves improving the long-term prognosis of patients with coronary artery disease by creating, implementing and evaluation of the optimal model of cardiological tele-rehabilitation combined with adequate treatment of coronary artery disease.

    Although clinical data demonstrate advantages of combining complete revascularization with optimal cardiac rehabilitation (CR) less than one-third of patients in European countries participate in cardiac rehabilitation programs. In addition, the major limitations of current CR programs are their short duration without long-term follow-up, lack of appropriate clinical and functional monitoring, and structural problems including geographic misdistribution of available programs.

    Therefore, in cooperation with Polish leaders in cardiovascular medicine, rehabilitation and medical software design we aim to introduce and evaluate the system of optimal cardiac telerehabilitation in addition to optimal treatment of coronary artery disease.

  • Sonata

    Sonata

    The influence of intramural cholesterol injection, systemic hypercholesterolemia and hyperglycemia on vascular response - insights into the development of a novel model of atherosclerotic plaque in swine

    This project is implemented entirely by American Heart of Poland Inc.

    AHP budget: eligible costs 316 thousand PLN, funding 316 thousand PLN

    Study period: 04.09.2014 - 03.06.2016

    The aim of this experimental study is to evaluate the vascular response to periadventitial injection of a cholesterol solution. We assume that the effect of a local administration of a proprietary cholesterol solution into the walls of the coronary and peripheral artery, under conditions of induced hyperglycemia and hypercholesterolemia, will allow us to obtain a unique and reproducible model of atherosclerotic plaque, with morphology similar to that seen in humans.

  • Phoenix

    Phoenix

    Stromal Cells and scaffolds as an alternative form of therapy for patiens with heart failure

    Project realised in the framework of the consortium composed of: Silesian Center for Heart Diseases (leader), American Heart of Poland Inc, Foundation of Cardiac Surgery and Development, Cardio-Med Silesia Ltd., Jagiellonian University in Krakow Faculty of Biochemistry, Biophysics and Biotechnology, The School of Pharmacy and Pharmaceutical Sciences and Trinity Biomedical Sciences Institute the University of Dublin Trinity College

    Total budget: eligible costs 15,47 million PLN, funding 14,2 million PLN

    AHP budget: eligible costs 2 million PLN, funding 0,8 million PLN

    Study period: 01.07.2015 - 30.06.2018

    The aim of the project is to carry out three unique clinical trials that will contribute to raise awareness about therapeutic potential and commercial use of MSC cells and scaffold. The project is dedicated to patients with severe, symptomatic ischemic heart failure who exhaust possibilities of model pharmacotherapy as well as interventional treatment (“no-option patients).

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